The US Food and Drug Administration (FDA) is accepting comments on a proposed rule which would allow the agency to amend its procedures of determining if a premarket notification for a food contact substance (FCN) is no longer effective. The proposed rule, if finalized, would provide manufacturers or suppliers an opportunity to address any safety concerns the FDA identifies before FDA determines that an FCN is no longer effective, rescinding the authorization.

The proposed rule would also provide FDA with additional reasons to make the determination that an FCN is no longer effective. These include:

• Instances in which the production, supply, or use of the food contact substance for its intended use has ceased or will cease;

• Use of a food contact substance identified in an FCN is authorized by a food additive regulation or covered by a threshold of regulation exemption.

The deadline to submit comments on this proposed rule is April 11, 2022.